About the Platform

The ELIXIR Italy Tools Platform supports the discovery, access, and use of bioinformatics tools and workflows for molecular data analysis across the life sciences. It promotes the adoption of community standards for software documentation, metadata, and interoperability, ensuring alignment with FAIR principles. The platform defines and disseminates best practices in software development, benchmarking, and sustainability. Strongly integrated with the ELIXIR Europe Tools Platform, it plays a key role in European benchmarking initiatives to evaluate tool performance across various biological domains.

Organization

Nationally, the platform is coordinated by a Coordinator and Deputy Coordinator who oversee its strategic direction. It brings together a wide network of researchers and technical experts from institutions active in structural bioinformatics, genomics, metagenomics, transcriptomics, proteomics, metabolomics, and systems biology. This diverse expertise enables collaborative development and maintenance of software tools and workflows that meet the analytical needs of the Italian and European life science community.

The platform’s activities include the provision and maintenance of computational workflows and tools supporting a wide range of molecular analyses. It emphasises interoperability, reproducibility, and long-term sustainability, aligning all developments with community-endorsed standards and FAIR data principles. It also connects tool development with training, ensuring the availability of relevant educational resources to support the adoption and effective use of these tools.

Focus Areas of Activity

  • Development and maintenance of bioinformatics tools and workflows
  • Interoperability and FAIR compliance of software resources
  • Scientific benchmarking and comparative evaluation of tools
  • Integration of tools with multi-omics data (genomics, proteomics, etc.)
  • Promotion of software development best practices and sustainability
  • Alignment of tools with training initiatives and resources

Synergy with ELIXIR Europe

The ELIXIR-IT Tools Platform is closely aligned with the ELIXIR Europe Tools Platform, actively contributing to joint activities and work packages. Italian experts participate in pan-European initiatives focused on benchmarking, tool evaluation, and software interoperability. This coordination ensures the integration of national tools into the broader ELIXIR ecosystem and reinforces the role of Italy in shaping the European bioinformatics infrastructure.

 

Leadership

Portrait of Castrense Savojardo
Platform Leader Castrense Savojardo
Università di Bologna
Portrait of Bruno Fosso
Platform Leader Bruno Fosso
Università di Bari

For industry

  • Advanced tools and workflows for molecular and multi-omics data analysis
  • Support for adapting tools to industrial applications and R&D pipelines
  • Expertise in workflow integration, reproducibility, and performance evaluation
  • Customisation of software solutions for biotech, pharma, and diagnostics sectors
  • Technology transfer and collaboration opportunities in computational biology
Learn more

Provided services

CONTIGuator

Command-line tool,  Web application

A bacterial genomes finishing tool for structural insights on draft genomes.

GATK-LODn

Command-line tool

This method increases specificity and sensitivity of GATK results for mutation…

I-MUTANT

Web application

Neural Network based Predictor of Protein stability Changes upon Single Point…

INGA

Web application,  Web API

Interaction Network GO Annotator protein function predictor.

MeDuSa

Command-line tool,  Web application

Algorithm for genome scaffoldin which exploits information obtained from a set…

PASTA

Command-line tool,  Web application

A web server predictor for amyloid aggregation propensity from protein…

PhD-SNP

Web application

Support Vector Machines based Predictor of human Deleterious Single Nucleotide…

PicNiC

Command-line tool

An effective pipeline to extract ensemble-level cancer progression models from…

REDItools

Command-line tool

Python scripts to detect RNA editing in deep transcriptome sequencing data…

Vinyl

Galaxy server for the functional annotation and prioritization of genetic…

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